News Center
A modern veterinary drug GMP pharmaceutical enterprise relying on high technology, integrating scientific research, development, production, sales and service
Cause Analysis and Countermeasures of Vaccine Immunization Failure
Release time:
2021-07-12
Cause Analysis and Countermeasures of Vaccine Immunization Failure
Vaccine immunization is an important means of prevention and control of infectious diseases, but immunization failures still occur from time to time. The reasons and corresponding countermeasures are as follows:
1. Live vaccines need to be stored below -15°C. If the transportation and storage are improper, the high temperature will cause failure;
Countermeasures: manufacturers need cold chain vaccine operation, users according to the requirements to save.
2. The inactivated vaccine needs to be stored at 2~8 ℃, which will lead to stratification under freezing conditions, especially in the northern winter. Once stratified, the vaccine cannot achieve the slow-release effect after immunization;
Countermeasures: Inactivated vaccines need to be stored in a cold room in the south (avoid freezing), and placed in a suitable temperature room in the north in winter.
3, metal ions, some antibiotics, disinfectants, etc. have an inactivation effect on the live vaccine, affecting the immune effect of the vaccine;
Countermeasures: to choose a special vaccine diluent, drinking water immunization with mineral water, etc., can not use tap water, and add skim milk and other protective agents.
4. Vaccines have a variety of immunization methods. Different vaccines have different immunization methods, and the immune effects produced are also different, and the immunization period is also different;
Countermeasures: adopt reasonable and efficient immunization methods; for example, fowlpox vaccine needs to use prickly seed, new branch two live vaccine spray immunization can provide better mucosal immunity, nasal drops and eye drops are more reliable than drinking water.
5, drinking water immune time is too long, especially in summer, resulting in poor vaccine immune effect;
Countermeasures: To calculate the water consumption, stop water for 1~2 hours first, and try to drink the diluted water of vaccine within 2 hours and ensure that the temperature is not too high. The drinking water pipeline should be cleaned before drinking water each time.
6. The use of antiviral drugs such as traditional Chinese medicine, some antibiotics, interferon, etc. before and after vaccine immunization can also lead to a decrease in the body's immune response to the vaccine, resulting in low antibody levels;
Countermeasures: vaccine immunization before and after 3 to 5 days can not use a variety of drugs that affect the production of antibodies.
7. Misoperation in the actual immunization process of vaccine, such as improper selection of syringe and injection site, can lead to immune failure;
Countermeasures: the corresponding training of the immunization team to ensure the correct use of vaccines.
8. There may be interference between some vaccines such as Newcastle disease and bursa live vaccine, so there must be an interval of 7 to 10 days between the two vaccines;
Countermeasures: A reasonable immunization program is the key to the effect of the vaccine.
9. When using vaccine to drink water for immunization, adding immune to the water is better, which can protect the vaccine activity and improve the body's immune response ability and antibody level in the body.
recommend today.
[product name]]
Common name: 1% premixed feed for livestock and poultry vitamins
Product: Immune Shuangjia
raw material composition]AND QB1
【sensory index]]This product is white or almost white powder.
[product features]]This product can not only significantly enhance the body's immune capacity, but also can quickly supplement the lack of vitamin E. Vitamin E breaks down intracellular peroxides, prevents oxidative damage to the cell membrane, and protects the biofilm from damage.
role and use]The main role of vitamin E is to regulate the body's oxidation process and promote gonadal development, significantly improve the body's immunity.
1, used to improve the body's immune system function, improve the effectiveness of vaccine immune prevention, especially for Newcastle disease, bursa of Fabricius, Chuanzhi vaccine protection. It can also reduce the toxicity of heavy metals such as mercury, lead and silver to the body.
2. It is used to eliminate the influence of various stress, immunosuppressive diseases, drugs, nutrition, interference and other adverse factors, activate the immune system, improve the immune response ability, and ensure the success of immunity.
3, for the lack of vitamin E, prevention and treatment of young animal white muscle disease and chick exudative diathesis, used to promote the growth and development of livestock and poultry, enhance reproductive capacity.
[scope of application]]Chickens, ducks, geese, pigs and other livestock and poultry animals.
method of use]Drink 50g of this product mixed with 25~50kg of water, and use it at the same time of immunization or drink it once in the morning and once in the evening before and after immunization for 3-5 days. The amount of water in hard areas can be appropriately increased.
[Note]]The standard has no provisions.
More news
Contact Us
Administrative service telephone:0532-85212368
Sales Advisory Phone:0086-532-85212381
E-mail:zhongrenyaoye@126.com
Address: No.6 Road, Jiaoxi Industrial Park, Jiaozhou City, Qingdao, Shandong Province
Qingdao Zhongren Animal Medicine Co., Ltd
Zhongren Aquatic Products