Pulp Fiber Speed Treatment (Experiment Report No. 3)

Indicated for the treatment of duck serositis, avian septicemic colibacillosis, air sacculitis, and other conditions.

Main ingredients: gatifloxacin mesylate, diphenoxylate hydrochloride, atropine sulfate, cefoperazone, sulbactam sodium, and others.

Product Features:

1. Broad-spectrum antibacterial activity; highly effective against avian septicemic Escherichia coli and Riemerella anatipestifer, improving intestinal health and reducing the feed-to-meat conversion ratio.

2. Relieve intestinal spasms and control diarrhea.

3. It is highly effective against avian air sacculitis (mixed infection with Escherichia coli), also known as E. coli–induced air sacculitis.

Usage and Dosage: Treatment: For mixed drinking, dissolve one sachet of this product in 1,200–1,500 jin of water and administer continuously for 3–5 days. Prevention: Dissolve one sachet of this product in 1,500–2,000 jin of water and administer continuously for 3–5 days.

Antimicrobial Susceptibility Test Report for the Submitted Sample

1. Sample Source Information

Customer Name

Address

Date

2024.6.23

1. Condition of the pathological material

The pathological materials consist of the pigeon’s heart, liver, and other major organs.

1. Pathological anatomy

The internal organs of pigeons were dissected and inoculated, followed by antimicrobial susceptibility testing.

1. Medication Recommendations

The isolated strains are highly susceptible to Jianggan Sushi, and also exhibit high sensitivity to Zhongren Gangqingbi, Jifuan, and chlortetracycline hydrochloride soluble powder. Therefore, treatment with Jianggan Sushi is recommended, supplemented by adjunctive therapies using Zhongren Gangqingbi, Jifuan, and chlortetracycline hydrochloride soluble powder; post‑treatment outcomes should be monitored. (Detailed treatment regimens for each group are provided in Section VI, Conclusions.)

1. Antimicrobial susceptibility testing

1. Sample No. 1

Drug name	Cassino	Amoxicillin Soluble Powder 10%	Chuan Li Ke	Chang An	Florfenicol Powder	Meiduola	Chicken Fu’an
Inhibition zone diameter (mm)	19	0	15	<10	0	12	17
Sensitivity	Gao Min	Uninspired	Gao Min	Hypoallergenic	Uninspired	Zhongmin	Gao Min
Drug name	Neomycin Sulfate Soluble Powder	Zhongren rod clear must	Kekesi	Tilmicosin Solution	Slowly call Dick.	Enrofloxacin solution	Zhihou Tailuo
Inhibition zone diameter (mm)	<10	18	<10	0	0	12	0
Sensitivity	Hypoallergenic	Gao Min	Hypoallergenic	Uninspired	Uninspired	Zhongmin	Uninspired
Drug name	Zhongren Mycoplasma Clean	Oxytetracycline Hydrochloride Soluble Powder	Chlortetracycline Hydrochloride Soluble Powder	Zhongren Jili'an	Pulp rod rapid treatment
Inhibition zone diameter (mm)	0	0	15	<10	26
Sensitivity	Uninspired	Uninspired	Gao Min	Hypoallergenic	Extremely sensitive

Summary of Test Results:

Method of determination: An inhibition zone diameter of ≥20 mm is classified as extremely susceptible; 15–20 mm as highly susceptible; 10–14 mm as moderately susceptible; <10 mm as poorly susceptible; and 0 mm as non‑susceptible.

Note: All of the above experiments were conducted with at least three replicates.

Experiment Summary;

The primary isolates from Sample No. 1 are highly sensitive to Jianggan Sushi (with inhibition zone diameters exceeding 20 mm) and moderately sensitive to Kasino, Chuanlilike, Jifuan, Zhongren Gangqingbi, and chlortetracycline hydrochloride soluble powder (with inhibition zone diameters ranging from 15 to 20 mm). It is recommended to use Jianggan Sushi for treatment, with Kasino, Chuanlilike, Jifuan, Zhongren Gangqingbi, and chlortetracycline hydrochloride soluble powder employed as adjunctive therapies.

Sample No. 2

Drug name	Cassino	Amoxicillin Soluble Powder 10%	Chuan Li Ke	Chang An	Florfenicol Powder	Meiduola	Chicken Fu’an
Inhibition zone diameter (mm)	0	0	0	1.1	0	<10	13
Sensitivity	Uninspired	Uninspired	Uninspired	Zhongmin	Uninspired	Hypoallergenic	Zhongmin
Drug name	Neomycin Sulfate Soluble Powder	Zhongren rod clear must	Kekesi	Tilmicosin Solution	Slowly call Dick.	Enrofloxacin solution	Zhihou Tailuo
Inhibition zone diameter (mm)	11	21	<10	0	0	14	0
Sensitivity	Zhongmin	Extremely sensitive	Hypoallergenic	Uninspired	Uninspired	Zhongmin	Uninspired
Drug name	Zhongren Mycoplasma Clean	Oxytetracycline Hydrochloride Soluble Powder	Chlortetracycline Hydrochloride Soluble Powder	Zhongren Jili'an	Pulp rod rapid treatment
Inhibition zone diameter (mm)	0	0	13	<10	25
Sensitivity	Uninspired	Uninspired	Zhongmin	Hypoallergenic	Extremely sensitive

Summary of Test Results:

Method of determination: An inhibition zone diameter of ≥20 mm is classified as extremely susceptible; 15–20 mm as highly susceptible; 10–14 mm as moderately susceptible; <10 mm as poorly susceptible; and 0 mm as non‑susceptible.

Note: All of the above experiments were conducted with at least three replicates.

Experiment Summary:

The primary isolates from Sample No. 2 exhibited extreme sensitivity to Zhongren Ganqingbi and Jianggan Sujizhi (as evidenced by inhibition zone diameters exceeding 20 mm), while showing moderate sensitivity to Jifuan, enrofloxacin solution, neomycin sulfate soluble powder, and chlortetracycline hydrochloride soluble powder (with inhibition zone diameters ranging from 10 to 15 mm). Treatment with Jianggan Sujizhi and Zhongren Ganqingbi is recommended.

3 Sample No. 2 (Old Pigeon)

Drug name	Cassino	Amoxicillin Soluble Powder 10%	Chuan Li Ke	Chang An	Florfenicol Powder	Meiduola	Chicken Fu’an
Inhibition zone diameter (mm)	0	0	0	11	<10	0	12
Sensitivity	Uninspired	Uninspired	Uninspired	Zhongmin	Hypoallergenic	Uninspired	Zhongmin
Drug name	Neomycin Sulfate Soluble Powder	Zhongren rod clear must	Kekesi	Tilmicosin Solution	Slowly call Dick.	Enrofloxacin solution	Zhihou Tailuo
Inhibition zone diameter (mm)	<10	21	14	0	0	12	0
Sensitivity	Hypoallergenic	Extremely sensitive	Zhongmin	Uninspired	Uninspired	Zhongmin	Uninspired
Drug name	Zhongren Mycoplasma Clean	Oxytetracycline Hydrochloride Soluble Powder	Chlortetracycline Hydrochloride Soluble Powder	Zhongren Jili'an	Pulp rod rapid treatment
Inhibition zone diameter (mm)	0	0	18	<10	23
Sensitivity	Uninspired	Uninspired	Gao Min	Hypoallergenic	Extremely sensitive

Summary of Test Results:

Method of determination: An inhibition zone diameter of ≥20 mm is classified as extremely susceptible; 15–20 mm as highly susceptible; 10–14 mm as moderately susceptible; <10 mm as poorly susceptible; and 0 mm as non‑susceptible.

Note: All of the above experiments were conducted with at least three replicates.

Experiment Summary:

Sample No. 2 (from an old pigeon) revealed that the predominant isolates were highly sensitive to Jianggan Sujizhi and Zhongren Ganqingbi, with inhibition zones exceeding 20 mm in diameter, and moderately sensitive to chlortetracycline hydrochloride soluble powder, exhibiting inhibition zones of approximately 15 mm in diameter. _~ 20 mm). It is recommended to treat with Jianggan Sushu and Zhongren Ganqingbi, and to use chlortetracycline hydrochloride soluble powder as an adjunctive therapy.

4 Sample No. 3

Drug name	Cassino	Amoxicillin Soluble Powder 10%	Chuan Li Ke	Chang An	Florfenicol Powder	Meiduola	Chicken Fu’an
Inhibition zone diameter (mm)	0	<10	0	<10	0	<10	21
Sensitivity	Uninspired	Hypoallergenic	Uninspired	Hypoallergenic	Uninspired	Hypoallergenic	Extremely sensitive
Drug name	Neomycin Sulfate Soluble Powder	Zhongren rod clear must	Kekesi	Tilmicosin Solution	Slowly call Dick.	Enrofloxacin solution	Zhihou Tailuo
Inhibition zone diameter (mm)	0	17	0	0	0	<10	0
Sensitivity	Uninspired	Gao Min	Uninspired	Uninspired	Uninspired	Hypoallergenic	Uninspired
Drug name	Zhongren Mycoplasma Clean	Oxytetracycline Hydrochloride Soluble Powder	Chlortetracycline Hydrochloride Soluble Powder	Zhongren Jili'an	Pulp rod rapid treatment
Inhibition zone diameter (mm)	0	0	20	<10	23
Sensitivity	Uninspired	Uninspired	Gao Min	Hypoallergenic	Extremely sensitive

Summary of Test Results:

Method of determination: An inhibition zone diameter of ≥20 mm is classified as extremely susceptible; 15–20 mm as highly susceptible; 10–14 mm as moderately susceptible; <10 mm as poorly susceptible; and 0 mm as non‑susceptible.

Note: All of the above experiments were conducted with at least three replicates.

The predominant isolates from Sample No. 3 exhibited extreme sensitivity to Jianggan Sushi and Jifuan (as evidenced by inhibition zone diameters exceeding 20 mm), while showing moderate sensitivity to Zhongren Ganqingbi and chlortetracycline hydrochloride soluble powder (with inhibition zone diameters ranging from 15 to 20 mm). It is recommended to use Jianggan Sushi and Jifuan for treatment, with Zhongren Ganqingbi and chlortetracycline hydrochloride soluble powder as adjunctive therapies.

Sample No. 5-4

Drug name	Cassino	Amoxicillin Soluble Powder 10%	Chuan Li Ke	Chang An	Florfenicol Powder	Meiduola	Chicken Fu’an
Inhibition zone diameter (mm)	0	0	0	<10	0	<10	14
Sensitivity	Uninspired	Uninspired	Uninspired	Hypoallergenic	Uninspired	Hypoallergenic	Zhongmin
Drug name	Neomycin Sulfate Soluble Powder	Zhongren rod clear must	Kekesi	Tilmicosin Solution	Slowly call Dick.	Enrofloxacin solution	Zhihou Tailuo
Inhibition zone diameter (mm)	<10	18	12	0	0	<10	0
Sensitivity	Hypoallergenic	Gao Min	Zhongmin	Uninspired	Uninspired	Hypoallergenic	Uninspired
Drug name	Zhongren Mycoplasma Clean	Oxytetracycline Hydrochloride Soluble Powder	Chlortetracycline Hydrochloride Soluble Powder	Zhongren Jili'an	Pulp rod rapid treatment
Inhibition zone diameter (mm)	0	0	20	<10	23
Sensitivity	Uninspired	Uninspired	Gao Min	Hypoallergenic	Extremely sensitive

Summary of Test Results:

Method of determination: An inhibition zone diameter of ≥20 mm is classified as extremely susceptible; 15–20 mm as highly susceptible; 10–14 mm as moderately susceptible; <10 mm as poorly susceptible; and 0 mm as non‑susceptible.

Note: All of the above experiments were conducted with at least three replicates.

The predominant isolates from sample No. 4 are highly sensitive to Jianggan Sushi (with inhibition zone diameters generally exceeding 20 mm) and moderately sensitive to Zhongren Ganqingbi and chlortetracycline hydrochloride soluble powder (with inhibition zone diameters ranging from 15 to 20 mm). Treatment is recommended with Jianggan Sushi and Jifuan, supplemented by Zhongren Ganqingbi and chlortetracycline hydrochloride soluble powder.

Sample No. 6-5

Drug name	Cassino	Amoxicillin Soluble Powder 10%	Chuan Li Ke	Chang An	Florfenicol Powder	Meiduola	Chicken Fu’an
Inhibition zone diameter (mm)	10	0	0	13	0	0	17
Sensitivity	Zhongmin	Uninspired	Uninspired	Zhongmin	Uninspired	Uninspired	Gao Min
Drug name	Neomycin Sulfate Soluble Powder	Zhongren rod clear must	Kekesi	Tilmicosin Solution	Slowly call Dick.	Enrofloxacin solution	Zhihou Tailuo
Inhibition zone diameter (mm)	0	16	<10	0	0	16	0
Sensitivity	Uninspired	Gao Min	Hypoallergenic	Uninspired	Uninspired	Gao Min	Uninspired
Drug name	Zhongren Mycoplasma Clean	Oxytetracycline Hydrochloride Soluble Powder	Chlortetracycline Hydrochloride Soluble Powder	Zhongren Jili'an	Pulp rod rapid treatment
Inhibition zone diameter (mm)	0	0	0	<10	23
Sensitivity	Uninspired	Uninspired	Uninspired	Hypoallergenic	Extremely sensitive

Summary of Test Results:

Method of determination: An inhibition zone diameter of ≥20 mm is classified as extremely susceptible; 15–20 mm as highly susceptible; 10–14 mm as moderately susceptible; <10 mm as poorly susceptible; and 0 mm as non‑susceptible.

Note: All of the above experiments were conducted with at least three replicates.

Experiment Summary:

The predominant isolates from sample No. 5 were highly sensitive to Jianggan Sushi (with inhibition zone diameters exceeding 20 mm) and moderately sensitive to Zhongren Gangqingbi, Jifuan, and enrofloxacin solution (with inhibition zone diameters ranging from 15 to 20 mm). Treatment with Jianggan Sushi is recommended, with Zhongren Gangqingbi, Jifuan, and enrofloxacin solution used as adjunctive therapies.

Sample No. 76

Drug name	Cassino	Amoxicillin Soluble Powder 10%	Chuan Li Ke	Chang An	Florfenicol Powder	Meiduola	Chicken Fu’an
Inhibition zone diameter (mm)	11	0	0	<10	<10	0	16
Sensitivity	Zhongmin	Uninspired	Uninspired	Hypoallergenic	Hypoallergenic	Uninspired	Gao Min
Drug name	Neomycin Sulfate Soluble Powder	Zhongren rod clear must	Kekesi	Tilmicosin Solution	Slowly call Dick.	Enrofloxacin solution	Zhihou Tailuo
Inhibition zone diameter (mm)	0	14	<10	0	0	<10	0
Sensitivity	Uninspired	Zhongmin	Hypoallergenic	Uninspired	Uninspired	Hypoallergenic	Uninspired
Drug name	Zhongren Mycoplasma Clean	Oxytetracycline Hydrochloride Soluble Powder	Chlortetracycline Hydrochloride Soluble Powder	Zhongren Jili'an	Pulp rod rapid treatment
Inhibition zone diameter (mm)	0	0	<10	16	24
Sensitivity	Uninspired	Uninspired	Hypoallergenic	Gao Min	Extremely sensitive

Summary of Test Results:

Method of determination: An inhibition zone diameter of ≥20 mm is classified as extremely susceptible; 15–20 mm as highly susceptible; 10–14 mm as moderately susceptible; <10 mm as poorly susceptible; and 0 mm as non‑susceptible.

Note: All of the above experiments were conducted with at least three replicates.

Experiment Summary:

The predominant isolates from sample No. 6 exhibited extreme sensitivity to Jianggan Sushi (with inhibition zone diameters exceeding 20 mm) and moderate sensitivity to Zhongren Jili’an and Jifuan (with inhibition zone diameters ranging from 15 to 20 mm). Treatment with Jianggan Sushi is recommended, with Zhongren Jili’an and Jifuan used as adjunctive therapies.

VI. Conclusion

Sample No. 1, Sample No. 4, and Sample No. 5: The predominant isolates from Sample No. 1 are highly sensitive to Jianggan Sushi; treatment with Jianggan Sushi is recommended, with Zhongren Ganqingbi, Jifuan, and chlortetracycline hydrochloride soluble powder used as adjunctive therapies. Sample No. 2 and Sample No. 2 (from older pigeons) are highly sensitive to Zhongren Ganqingbi and Jianggan Sushi; treatment with Jianggan Sushi and Zhongren Ganqingbi is advised, with chlortetracycline hydrochloride soluble powder as an adjunctive therapy. Sample No. 3: The predominant isolates are highly sensitive to Jianggan Sushi and Jifuan; treatment with Jianggan Sushi and Jifuan is recommended, with Zhongren Ganqingbi and chlortetracycline hydrochloride soluble powder employed as adjunctive therapies.

Treatment recommendations: The isolated strain is highly susceptible to Jianggan Sushi Zhi; drugs such as Zhongren Ganqingbi, Jifuan, and chlortetracycline hydrochloride soluble powder all exhibit high sensitivity. Therefore, we recommend using Jianggan Sushi Zhi for treatment, with Zhongren Ganqingbi, Jifuan, and chlortetracycline hydrochloride soluble powder as adjunctive therapies. Monitor the therapeutic response after administration.