Characteristics and prevention of variant bursa of Fabricius
2023-08-13
Qingdao Zhongren Animal Medicine Co., Ltd
Zhongren kinetic drug
Bursa disease is an acute, highly contagious disease in chicks,2 Within weeks of age, the bursa lymphoid tissue of young chickens is invaded, resulting in deep immunosuppression,3~6 week-old young chicken susceptible, acute death, mortality15%~50%,Spiking death curve, super-virulent strain infection mortality rate up.70%The emergence of variant strains and super-virulent strains, the original standard vaccine with good immune effect can not provide complete protection.
Bursal disease virus is very resistant to acid (pH 3), lipid solvents, various disinfectants and heat (60℃30min) processing. Under ultraviolet light and sunlight, the tolerance is also very strong,Dung or fodder, etc., removed from a sick chicken coop, after passing through50dAfter that, it is still contagious.
Epidemic characteristics of bursal disease
The occurrence of bursal disease is related to the age of day:18Days of age caused immunosuppression;18It causes morbidity, mortality and immunosuppression after days of age.12－24Weeks gradually shrink and disappear, losing susceptibility to bursal disease.
Immunization has greatly reduced the mortality of bursal disease, butImmunosuppression Can Cause Huge Indirect Economic Losses. Maternal antibodies can give chicks some protection, but also interfere with the production of active immunity. Humoral immunity often plays a leading role.
Post-infection flock performance
Poor production performance, increased mortality, light weight, uneven growth, increased feed consumption, and atrophy of the bursa of Fabricius
The spleen is larger than the bursa of Fabricius(When normal,4The bursa of Fabricius is larger than the spleen)Strong respiratory response(Escherichia coli,Mycoplasma in laying hens)
disease outbreak(Escherichia coli,Newcastle disease,infectious bronchitis)
How to prevent and treat bursal disease?
1Disinfection of the environment, especially the brooding room. Disinfection of the environment, chicken coops, appliances, cages,4~6hAfter that, thoroughly clean and rinse, and then2~3 Disinfection. It takes a while for chicks to go from vaccination to antibody production, so immunized chicks must be placed in a thoroughly disinfected brood to preventIBDVearly infection. If rightIBDVPollution of the environment does not take strict, serious, thorough disinfection measures in the environment a large numberIBDVIt will damage the bursa of the chick before the vaccine works, and no good vaccine can provide effective immune protection.
2Injectable at onsetIBDThe high-free egg yolk liquid isIBDEgg yolk antibody. Egg yolk antibody has good safety and quick effect.
In the use of live vaccines in a dilemma (virulence is too weak, it is difficult to break through the interference of maternal antibodies; virulence is too strong, easy to cause immunosuppression), inactivated vaccine effect is slow, the use of yolk antibody may become an emergency controlIBDThe most effective route of acute infection. Emergency vaccinations.
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