How to improve the immune effect of vaccines

2020-04-17

Qingdao Zhongren Animal Medicine Co., Ltd

Zhongren kinetic drug

In the process of poultry breeding, in order to prevent the occurrence of epidemic diseases, it is necessary to vaccinate poultry many times. However, due to various reasons, the effect is often not ideal, and even the immunization fails. There are many reasons. The following points are conducive to improving the immune effect of poultry, for the majority of aquaculture industry colleagues reference.

1) Ensure the quality of the vaccine

The purchased vaccine should be guaranteed to have sufficient effect, and the vaccine that exceeds the validity period or becomes invalid cannot be used. During the transportation, storage and use of vaccines, high temperature and direct exposure should be avoided.

2, reasonable arrangement of vaccination time

The timing of immunization of poultry is determined by the prevalence of infectious diseases and the actual antibody levels of chickens. For chickens susceptible to Marek's disease and infectious bronchitis, it is best to vaccinate at the age of one day to prevent recessive infection before vaccination. For Newcastle disease and infectious bursal disease, the first exemption date should be determined according to the maternal antibody.

3, the dilution should be appropriate

Some vaccines are diluted with special dilutions, such as Marek's disease vaccine, and cannot be replaced with others. For no special requirements of the vaccine, available sterile saline, distilled water or cold water dilution.

Avoid interactions between vaccines

Poultry are vaccinated against a variety of vaccines throughout their lives. When several vaccines are used at the same time (except for multiple vaccines) or when the vaccination time is similar, it sometimes interferes. Such as transmission branch vaccine, coccidia vaccine, fowlpox vaccine will interfere with Newcastle disease immunity. Vaccination of Newcastle disease attenuated vaccine shall not be inoculated within one week of transmission of attenuated vaccine; used transmission of attenuated vaccine shall not be inoculated within two weeks of Newcastle disease attenuated vaccine. The interference factors of fowlpox will affect about 10 days. The vaccination time should be balanced and a scientific immunization program should be developed.

5, careful use of drugs

Do not use disinfectants, antibiotics or antiviral drugs for 2 days before and after immunization, otherwise it will kill the live vaccine and destroy the antigenicity of the inactivated vaccine. In addition, certain antibiotics sulfonamides, furansChloramphenicolDrugs will affect the body's lymphocyte immune function, inhibit antibody production, so it should be used with caution.

6. Proper use of immune potentiators

At the time of immunization, you can choose some drugs that can enhance the immune effect of the vaccine (e. g,immune double good:Main ingredients VE, levamisole, skimmed milk powder, etc;Qizhen Zengfree Granules: Main ingredients: Astragalus polysaccharide, Ligustrum lucidum, Epimedium, etc.) used at the same time, which reduces the hardness of the vaccine drinking water, eliminates the influence of some heavy metals, can also enhance the immune effect of the vaccine, help promote the rapid generation of antibodies, and also has a purifying effect on some immunosuppressive diseases.

7、correct inoculation operation.

There are many immunization methods, such as intramuscular injection, drinking water, eye drops, nasal drops and so on. Different methods, the effect is different, the dose requirements are not the same, when inoculation can not be.to take it for granted,Change at willMethods and Dosages. Freeze-dried seedlings are all live seedlings, which are vacuum sealed during production. They cannot be directly exposed to the air and opened directly during use. When drinking water for immunization, a small amount of water can be prepared first and the vaccine can be opened in water;Intramuscular injection, eye drops, nasal dropsWhen diluting the vaccine in other ways, a syringe should be used to cooperate with the operation. Opening the vaccine bottle directly will reduce the effect of the vaccine. Attention should also be paid to the immunization time of any unit vaccine. The vaccine should be used up as soon as possible after dilution and is now used up.